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Ragab,, S., El-Kholy, A. (2007). ANTIOXIDANT PROPERTIES OF BOVINE COLOSTRUM AND ITS MAIN BIOACTIVE CONSTITUENTS OF LACTOFERRIN AND LACTOPEROXIDASE. Journal of Animal and Poultry Production, 32(3), 1731-1741. doi: 10.21608/jappmu.2007.219441
S. S. Ragab,; A. F. El-Kholy. "ANTIOXIDANT PROPERTIES OF BOVINE COLOSTRUM AND ITS MAIN BIOACTIVE CONSTITUENTS OF LACTOFERRIN AND LACTOPEROXIDASE". Journal of Animal and Poultry Production, 32, 3, 2007, 1731-1741. doi: 10.21608/jappmu.2007.219441
Ragab,, S., El-Kholy, A. (2007). 'ANTIOXIDANT PROPERTIES OF BOVINE COLOSTRUM AND ITS MAIN BIOACTIVE CONSTITUENTS OF LACTOFERRIN AND LACTOPEROXIDASE', Journal of Animal and Poultry Production, 32(3), pp. 1731-1741. doi: 10.21608/jappmu.2007.219441
Ragab,, S., El-Kholy, A. ANTIOXIDANT PROPERTIES OF BOVINE COLOSTRUM AND ITS MAIN BIOACTIVE CONSTITUENTS OF LACTOFERRIN AND LACTOPEROXIDASE. Journal of Animal and Poultry Production, 2007; 32(3): 1731-1741. doi: 10.21608/jappmu.2007.219441

ANTIOXIDANT PROPERTIES OF BOVINE COLOSTRUM AND ITS MAIN BIOACTIVE CONSTITUENTS OF LACTOFERRIN AND LACTOPEROXIDASE

Article 4, Volume 32, Issue 3, March 2007, Page 1731-1741  XML PDF (632.99 K)
Document Type: Original Article
DOI: 10.21608/jappmu.2007.219441
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Authors
S. S. Ragab,1; A. F. El-Kholy2
1Food Science and Nutritional depart. Faculty Home Economics, Minofiya University
2Animal Production Depart. Faculty of Agric. Cairo University.
Abstract
Bovine colostrum and its protective bioactive constituents lactoferrin and lactoperoxidase have been shown to prevent oxidant -induced injury of endothelial cells. The aim of present  study was to determine the effects of a dietary bovine colostrum on the generation of  hydrogen peroxide (H2O2) and superoxide anion(O2) and the activity of three antioxidant enzymes in a bovine pulmonary artery endothelial cell line (PAEC). All of the examined colostrum fraction forms exhibited a clear and potent antioxidant activity by increasing significantly the activity of all antioxidant enzymes in a dose and time-dependent fashion. The results suggested that dietary bovine colostrum and its constituents may be effective antioxidants in preventing or treating endothelial ceil injury associated with reactive oxygen species (ROS). 
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