AFLATOXICOSIS IN POULTRY: 2- EFFICACY OF HYDRATED SODIUM CALCIUM ALUMINOSILICATE AND YEAST CELL WALL TO AMELIORATE THE ADVERSE EFFECTS OF AFLATOXIN ON BROILER TISSUES

Shebl, M. A.; Motawe, H. F. A.; Yehia, T.; Abo Hagger, Amal A.; Ahmed, Kawkab A.

doi:10.21608/jappmu.2010.86215

AFLATOXICOSIS IN POULTRY: 2- EFFICACY OF HYDRATED SODIUM CALCIUM ALUMINOSILICATE AND YEAST CELL WALL TO AMELIORATE THE ADVERSE EFFECTS OF AFLATOXIN ON BROILER TISSUES

Document Type : Original Article

Authors

¹ Regional Center for Food and Feed, Agric. Res. Center, Giza, Egypt.

² Dept. of Pathology , Faculty of Vet. Med., Cairo Univ., Giza, Egypt.

10.21608/jappmu.2010.86215

Abstract

Hydrated Sodium Calcium Aluminosilicate (HSCAS) and Yeast (Saccharomyces cerevisiae) cell wall (YCW) were evaluated for their ability to reduce the deleterious effects of aflatoxin (AFT) in broiler diets. They were incorporated singly or in combination into a diet containing total AFT 211.88 µg / kg feed. Aflatoxin induced vacuolar degeneration of hepatocytes, thickening in the wall of bile duct associated with leucocytic cells infiltration in the portal triad, kidneys showed necrobiotic changes of renal tubular epithelium with pyknosis of their nuclei and hypercllularity of glomerular tufts. Brain of chickens showed more or less similar histopathological changes described as necrosis of neurons , neuronophagia of necrotic neurons and necrosis of purkinje cells of the cerebellum .The levels of AFT residue in the treated groups were varied in type and amount from group to group as well as from tissue to tissue. Also aflatoxin induced an elevation in the levels of the elements AS , Pb and Zn in the tested tissues. Slight histopathological improvement was recorded in the previous tissues after the contaminated diet was incorporated singly or in combination with HSCAS and YCW. The most noticeable record was the drastic elevation in level of Al in the tissues of groups which were treated with HSCAS. The same groups revealed higher levels of AFT residue in meat and liver .Theaddition of YCW didn't induce noticeable improvement. Data concluded that, no clear improvements in the tested parameter were recorded after the contaminated diets were incorporated with the recommended dose of HSCAS and YCW , singly or in combination, during aflatoxicosis. More specific researchis needed to clarify their unknown undesired effects on broiler.